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Valcavi R, Jordan V, Dieguez C, John R, Manicardi E, Portioli I, Rodriguez-Arnao MD, Gomez-Pan A, Hall R, Scanlon MF

Lamas GA, Bhatnagar A, Jones MR, et al

Goldstein JL, DeBose-Boyd RA, Brown MS

This section highlights key examples of TCM-derived metabolites that have made significant strides toward clinical translation, including berberine, quercetin, and the polyherbal Qili Qiangxin capsule, focusing on trial data, outcomes, and safety profiles ( 3.1 Clinical evidence and translational successes As a single-metabolite supplement, berberine has been used in East Asia for metabolic and cardiovascular health for decades, and Western interest has increased in recent years (Song et al., 2020)

As a result, we used 400 mM OA to induce steatosis in all our experiments

Proper injection technique, site rotation, and allowing the medication to reach room temperature before injection (if recommended in your product's IFU) can minimize these effects